Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 10/20 | 0.59 |
| ▸ | PPARA | Q07869 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392906 | 0.89 | FFAR1 (0.68) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL4030957 | 0.88 | FFAR1 (0.70) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL4032011 | 0.88 | FFAR1 (0.70) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL7736876 | 0.87 | PPARG (0.74) | PPARGPPARA | |
| SCHEMBL6157895 | 0.86 | FFAR1 (0.68) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL9721982 | 0.86 | KDR (0.71) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL14302921 | 0.85 | PPARG (0.61) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL14281856 | 0.85 | PPARG (0.61) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL6248263 | 0.85 | KDR (0.63) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL4850325 | 0.84 | FFAR1 (0.69) | FFAR1KDRPPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177353-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |