Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372015 | 1.00 | TBXAS1 (0.57) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| Hydrochloric Acid SCHEMBL10986112 | 0.99 | TBXAS1 (0.56) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| Hydrochloric Acid SCHEMBL10373076 | 0.99 | TBXAS1 (0.56) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| SCHEMBL7803212 | 0.82 | CYP11B2 (0.59) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| SCHEMBL9768495 | 0.80 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HSD17B10TACR1 | |
| SCHEMBL10373326 | 0.80 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HSD17B10TACR1 | |
| SCHEMBL10375582 | 0.80 | TBXAS1 (0.76) | TBXAS1CYP11B2ALDH1A1HSD17B10TACR1 | |
| SCHEMBL7809643 | 0.79 | CYP11B2 (0.49) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| SCHEMBL7803071 | 0.77 | MAPT (0.54) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 | |
| SCHEMBL10373114 | 0.76 | TBXAS1 (0.55) | TBXAS1POLBMAPTSMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129051-B1 | SUBSTITUTED INDOLES | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| US-4511573-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0129051-A2 | Substituted indoles | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |