Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803212 | 0.82 | CYP11B2 (0.59) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| SCHEMBL7803165 | 0.81 | CYP11B2 (0.48) | CYP11B2MAPTSMN1; SMN2POLBTBXAS1 | |
| SCHEMBL10372015 | 0.79 | TBXAS1 (0.57) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| SCHEMBL10372017 | 0.79 | TBXAS1 (0.57) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| Hydrochloric Acid SCHEMBL10986112 | 0.78 | TBXAS1 (0.56) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| Hydrochloric Acid SCHEMBL10373076 | 0.78 | TBXAS1 (0.56) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| SCHEMBL7803071 | 0.76 | MAPT (0.54) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| SCHEMBL7811410 | 0.75 | LMNA (0.71) | CYP11B2MAPTSMN1; SMN2POLBTEK | |
| SCHEMBL7807904 | 0.75 | CYP11B2 (0.46) | CYP11B2MAPTSMN1; SMN2POLBTBXAS1 | |
| SCHEMBL7803160 | 0.71 | APP (0.56) | MAPTSMN1; SMN2POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |