SCHEMBL1037299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5501998	0.78	HDAC3 (0.38)	TNFGRM2HDAC3HDAC1HDAC6
	SCHEMBL1039402	0.77	DDR1 (0.41)	TNFMCL1KDM4EMEN1MAPT
	SCHEMBL1035977	0.76	TNF (0.56)	TNFKDM4EMAPT
	SCHEMBL15265084	0.76	KDM4E (0.58)	TNFGRM2HDAC3HDAC1HDAC6
	SCHEMBL9922460	0.75	TXNRD1 (0.46)	HTR2AHTR2CTXNRD1TXNRD3TXNRD2
	SCHEMBL2611306	0.74	HDAC6 (0.52)	MCL1HDAC3HDAC1HDAC6
	SCHEMBL2116182	0.74	MCL1 (0.53)	TNFMCL1HDAC3HDAC1HDAC6
	SCHEMBL2619282	0.73	HDAC6 (0.50)	MCL1HDAC3HDAC1HDAC6
	SCHEMBL2116350	0.73	HDAC6 (0.55)	TNFMCL1HDAC3HDAC1HDAC6
	SCHEMBL13222875	0.72	TNF (0.47)	TNFGRM2HDAC6CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.