Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104152 | 0.87 | KDM4E (0.53) | GPR119NPC1KDM4ERAB9AMAPT | |
| SCHEMBL106591 | 0.85 | ALDH1A1 (0.41) | NPC1KDM4ERAB9AMAPTHPGD | |
| SCHEMBL16549837 | 0.84 | GPR119 (0.39) | GPR119NPC1KDM4ERAB9AMAPT | |
| SCHEMBL103405 | 0.84 | KMT2A (0.46) | GPR119KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL16549836 | 0.84 | GPR119 (0.39) | GPR119NPC1KDM4ERAB9AMAPT | |
| SCHEMBL2683352 | 0.77 | HDAC1 (0.49) | GPR119NPC1KDM4ERAB9AMAPT | |
| SCHEMBL103892 | 0.75 | SMN1; SMN2 (0.47) | GPR119NPC1KDM4ERAB9AMAPT | |
| SCHEMBL103471 | 0.73 | ALDH1A1 (0.43) | NPC1KDM4ERAB9AMAPTHPGD | |
| SCHEMBL20333136 | 0.73 | HDAC1 (0.52) | GPR119KDM4EHDAC1HDAC6TSHR | |
| SCHEMBL103470 | 0.73 | ALDH1A1 (0.43) | NPC1KDM4ERAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |