Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369446 | 0.82 | CYP1A2 (0.53) | HSD11B1KMOCYP1A2CYP3A4ALOX15 | |
| SCHEMBL3366336 | 0.79 | BACE1 (0.51) | HSD11B1KMOACP1CYP1A2CYP3A4 | |
| SCHEMBL8818449 | 0.78 | CYP1A2 (0.50) | ACP1CYP1A2CYP3A4ALOX15TSHR | |
| SCHEMBL20782565 | 0.77 | HSD11B1 (0.51) | HSD11B1KMOACP1CYP1A2CYP3A4 | |
| SCHEMBL25428915 | 0.76 | KMO (0.60) | HSD11B1KMOACP1CYP1A2CYP3A4 | |
| SCHEMBL8450245 | 0.76 | CCR1 (0.58) | CCR1CCR8 | |
| SCHEMBL10374376 | 0.75 | CCR1 (0.62) | CCR1CCR8 | |
| SCHEMBL13556450 | 0.75 | KMO (0.44) | HSD11B1KMOACP1CYP1A2CYP3A4 | |
| SCHEMBL1107908 | 0.75 | KMO (0.44) | HSD11B1KMOACP1CYP1A2CYP3A4 | |
| SCHEMBL10755091 | 0.75 | KMO (0.48) | HSD11B1KMOACP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244130-B1 | PROCESS FOR MAKING 6-ARYL-2-METHYL PYRIDINES | ROHM AND HAAS COMPANY (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4804761-A | Process for making 6-aryl-2-methylpyridines | ROHM AND HAAS COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0244130-A2 | Process for making 6-aryl-2-methyl pyridines | ROHM AND HAAS COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0243101-A2 | Insecticidal 6-aryl-pyridine thiosemicarbazones | ROHM AND HAAS COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4696938-A | Insecticidal 6-aryl-pyridine thiosemicarbazones | ROHM AND HAAS COMPANY (US) | 1987-09-29 | — | — | US | disclosed |