Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.45 |
| ▸ | HNF4A | P41235 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217459 | 0.84 | PTPN1 (0.50) | PLA2G2APLA2G4ATBK1ACMSDHNF4A | |
| SCHEMBL23610605 | 0.83 | NPC1 (0.52) | PLA2G2APLA2G4ATBK1KDM4EMAPT | |
| SCHEMBL1444187 | 0.83 | MCL1 (0.63) | PLA2G2APLA2G4AMCL1KDM4EMEN1 | |
| SCHEMBL31110302 | 0.80 | NPC1 (0.50) | PLA2G2APLA2G4ATBK1ACMSDKDM4E | |
| SCHEMBL647309 | 0.79 | KMT2A (0.51) | MCL1KDM4EMAPTCALM1PKM | |
| SCHEMBL29502948 | 0.79 | KMT2A (0.51) | MCL1KDM4EMAPTCALM1PKM | |
| SCHEMBL6239909 | 0.79 | KDM4E (0.45) | PLA2G2APLA2G4ATBK1MCL1KDM4E | |
| SCHEMBL10563382 | 0.79 | PLA2G2A (0.53) | PLA2G2APLA2G4ATBK1KDM4EMAPT | |
| SCHEMBL6241692 | 0.77 | KDM4E (0.53) | PLA2G2APLA2G4ATBK1KDM4EMAPT | |
| SCHEMBL10370983 | 0.77 | GPR35 (0.44) | MCL1KDM4EMAPTMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |