Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610605 | 0.86 | NPC1 (0.52) | PTPN1TBK1PLA2G2APLA2G4AL3MBTL1 | |
| SCHEMBL8201626 | 0.84 | L3MBTL1 (0.60) | L3MBTL1KDM4ETSHRMAPTHPGD | |
| SCHEMBL8401426 | 0.84 | MCL1 (0.61) | KDM4EHPGDHSD17B10MCL1CA1 | |
| SCHEMBL10374396 | 0.84 | PLA2G2A (0.47) | PTPN1TBK1PLA2G2APLA2G4AKDM4E | |
| SCHEMBL31110302 | 0.83 | NPC1 (0.50) | TBK1PLA2G2APLA2G4AKDM4EMAPT | |
| SCHEMBL3610930 | 0.83 | PTPN1 (0.59) | PTPN1L3MBTL1KDM4ETSHRGLA | |
| SCHEMBL1444187 | 0.83 | MCL1 (0.63) | PLA2G2APLA2G4AL3MBTL1KDM4ETSHR | |
| SCHEMBL9217430 | 0.81 | TBK1 (0.46) | PTPN1TBK1L3MBTL1KDM4EHPGD | |
| SCHEMBL9219841 | 0.79 | MCL1 (0.63) | KDM4EHPGDHSD17B10MCL1CA1 | |
| SCHEMBL9212323 | 0.79 | L3MBTL1 (0.51) | L3MBTL1KDM4EMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |