SCHEMBL1037481

SCHEMBL1037481

CCCCCCP(=O)(O)CCC(=O)OCCCO

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.50
NAAA Q02083 1/20 0.46
HTR2C P28335 1/20 0.45
DNM1 Q05193 1/20 0.43
P2RY10 O00398 4/20 0.42
GPR34 Q9UPC5 2/20 0.42
LPAR3 Q9UBY5 3/20 0.42
LPAR2 Q9HBW0 1/20 0.42
MGLL Q99685 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290937 0.89 DGKA (0.55) DGKANAAAHTR2CDNM1LPAR3
SCHEMBL1036795 0.86 MGLL (0.48) DGKANAAAHTR2CDNM1P2RY10
SCHEMBL9290907 0.85 DGKA (0.48) DGKANAAAHTR2CDNM1P2RY10
SCHEMBL1037012 0.82 DGKA (0.48) DGKANAAAHTR2CDNM1P2RY10
SCHEMBL1036029 0.81 ACHE (0.41) DGKANAAAHTR2CP2RY10GPR34
SCHEMBL8844811 0.81 DGKA (0.56) DGKANAAAHTR2CDNM1P2RY10
SCHEMBL8844601 0.81 DGKA (0.56) DGKANAAAHTR2CDNM1P2RY10
SCHEMBL769295 0.80 DGKA (0.77) DGKANAAAHTR2CDNM1MGLL
SCHEMBL2532999 0.80 DGKA (0.77) DGKANAAAHTR2CDNM1MGLL
SCHEMBL770067 0.80 DGKA (0.77) DGKANAAAHTR2CDNM1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832596-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components CLARIANT FINANCE BVI LTD (VG) 2011-01-26 EP claimed
US-20070210288-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components CLARIANT INTERNATIONAL LTD 2007-09-13 US claimed
EP-1832596-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP claimed
EP-1832596-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components CLARIANT FINANCE BVI LTD (VG) 2011-01-26 EP disclosed
US-7485745-B2 Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components CLARIANT INTERNATIONAL LTD. (CH) 2009-02-03 US disclosed
US-20070210288-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components CLARIANT INTERNATIONAL LTD 2007-09-13 US disclosed
EP-1832596-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070210288-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components ALKBH3, FFAR3, EBP DGKA 108/4885NAAA 3904/4885HTR2C 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.