Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | YES1 | P07947 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494268 | 0.93 | KCNA5 (0.65) | KCNA5KCNH2TBXA2RHDAC3HDAC4 | |
| SCHEMBL10374845 | 0.90 | LMNA (0.52) | KCNA5KCNH2HDAC3HDAC4HDAC1 | |
| SCHEMBL10374719 | 0.90 | KCNA5 (0.58) | KCNA5KCNH2HDAC3HDAC4HDAC1 | |
| SCHEMBL698959 | 0.85 | KCNA5 (0.71) | KCNA5KCNH2TBXA2RHDAC3HDAC4 | |
| SCHEMBL9814888 | 0.85 | KCNA5 (0.56) | KCNA5KCNH2TBXA2RHDAC3HDAC4 | |
| SCHEMBL10372455 | 0.84 | TBXAS1 (0.49) | KCNA5TBXA2RTBXAS1 | |
| SCHEMBL10371704 | 0.84 | KCNA5 (0.55) | KCNA5KCNH2TBXA2RMCL1 | |
| SCHEMBL698228 | 0.83 | KCNA5 (0.64) | KCNA5KCNH2TBXA2RHDAC3HDAC4 | |
| SCHEMBL9362957 | 0.82 | KCNA5 (0.54) | KCNA5KCNH2HDAC3HDAC4HDAC1 | |
| SCHEMBL9363306 | 0.82 | KCNA5 (0.65) | KCNA5KCNH2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251011-B1 | INDOLYL PROPIONIC ACIDS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4843091-A | Indolylpropionic acids, compositions of, and use thereof to inhibit thrombocyte aggregation | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |