Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376617 | 0.83 | PLAT (0.35) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10375472 | 0.80 | GABRA1 (0.43) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10376245 | 0.80 | GABRA1 (0.33) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9687528 | 0.80 | OPRL1 (0.32) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7491336 | 0.79 | GABRP (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10374196 | 0.78 | GABRA1 (0.39) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9687853 | 0.77 | MEN1 (0.36) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9688595 | 0.76 | OPRL1 (0.37) | OPRL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10374410 | 0.75 | KMT2A (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9534379 | 0.74 | MAPT (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161574-B1 | NEW B-CARBOLINE-3-OXADIAZOLYL DERIVATIVES, METHOD OF PREPARING THE SAME AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4645773-A | MUSCLE RELAXANTS, ANTIEPILEPTIC AGENTS, SEDATIVES, TRANQUILIZERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-02-24 | — | — | US | disclosed |