SCHEMBL10376271

SCHEMBL10376271

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10376223 0.97 LMNA (0.38) LMNA
SCHEMBL8076123 0.90 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL10378404 0.78 KDM4E (0.41)
SCHEMBL28663277 0.75 LMNA (0.36) LMNA
SCHEMBL10378420 0.75
SCHEMBL62551 0.74 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL10399633 0.74 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL9847525 0.74 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL17140178 0.73
SCHEMBL10376221 0.71 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1990010096-A1 A METHOD OF CLEANING USING HYDROCHLOROFLUOROCARBONS ALLIED-SIGNAL INC. (US) 1990-09-07 WO disclosed
US-4947881-A Method of cleaning using hydrochlorofluorocarbons ALLIED-SIGNAL INC. (US) 1990-08-14 US disclosed