Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.58 |
| ▸ | G6PD | P11413 | 5/20 | 0.57 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205847 | 0.85 | G6PD (0.62) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL1613852 | 0.80 | G6PD (0.68) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL12179299 | 0.79 | CASP3 (0.65) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL2963555 | 0.78 | CASP3 (0.68) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL17948304 | 0.77 | CASP3 (0.72) | CASP3KAT2AKAT2B | |
| SCHEMBL11278746 | 0.77 | CASP3 (0.74) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL9886495 | 0.76 | DTYMK (0.74) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL13606221 | 0.76 | G6PD (0.72) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL19240713 | 0.76 | CASP3 (0.66) | CASP3G6PDKAT2AKAT2B | |
| SCHEMBL12370925 | 0.75 | KAT2A (0.67) | CASP3G6PDKAT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236930-B1 | AROMATIC 2-AMINOALKYL-1,2-BENZOISOTHIAZOL-3(2H)ONE-1,1-DIOXIDE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-10-31 | — | — | EP | disclosed |
| EP-0236930-A1 | Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4190663-A | Anti-thrombotic 1,2-benzisothiazolin-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4156729-A | ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |