SCHEMBL11278746

SCHEMBL11278746

O=c1c2ccccc2sn1CCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 6/20 0.74
FAAH O00519 1/20 0.70
MGLL Q99685 1/20 0.70
KAT2A Q92830 1/20 0.68
KAT2B Q92831 1/20 0.68
G6PD P11413 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24836229 0.92 FAAH (0.76) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL24836231 0.92 FAAH (0.81) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL24836228 0.90 FAAH (0.84) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL24690027 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL20350783 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL28308141 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL9376161 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL8070856 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL8356552 0.89 CASP3 (0.66) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL358740 0.89 FAAH (0.77) CASP3FAAHMGLLKAT2AKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024008788-A1 USE OF EBSELEN OR ONE OF THE DERIVATIVES THEREOF TO TREAT MITOCHONDRIAL PATHOLOGIES OR DYSFUNCTIONS ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES (FR) 2024-01-11 WO disclosed
EP-4265601-A2 USE OF BENZISOSELAZOLE DERIVATIVE FOR ANTI-CORONAVIRUS AND CONTROL OF INTERSTITIAL LUNG DISEASE (ILD) RELATED TO CORONAVIRUS Shanghai Yuanxi Medicine Corp. (CN) 2023-10-25 EP disclosed
WO-2023279426-A1 POLYSUBSTITUTED SELENIUM-CONTAINING CYCLOPENT(HEX)ENE FRAMEWORK DERIVATIVE AND SYNTHESIS METHOD THEREFOR 苏州大学 2023-01-12 WO disclosed
WO-2023277584-A1 COMPOSITION FOR REMOVING SENSESCENT CELLS COMPRISING SELENIUM COMPOUND AS ACTIVE INGREDIENT (주)라이프신약 2023-01-05 WO disclosed
US-4350702-A 2-SUBSTITUTED BENZISOTHIAZOLONES BEECHAM GROUP LIMITED (GB) 1982-09-21 US disclosed
US-4243669-A ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1981-01-06 US disclosed
US-4212872-A ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1980-07-15 US disclosed
US-4212979-A ANTITHROMOGENIC BEECHAM GROUP LIMITED (GB) 1980-07-15 US disclosed
US-4113728-A ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1978-09-12 US disclosed