Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 4/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324895 | 0.93 | LTA4H (0.40) | SYK | |
| SCHEMBL7328746 | 0.82 | SYK (0.38) | SYKKLK5CTSSCTSKSIGMAR1 | |
| SCHEMBL10378291 | 0.76 | LTA4H (0.39) | SYK | |
| SCHEMBL7322023 | 0.72 | TLR2 (0.33) | — | |
| SCHEMBL10378284 | 0.71 | LTA4H (0.45) | SYKREN | |
| SCHEMBL7324667 | 0.69 | ALOX5 (0.41) | — | |
| SCHEMBL7329315 | 0.69 | ALOX5 (0.37) | — | |
| SCHEMBL7326123 | 0.68 | SYK (0.48) | SYKKLK5CTSKCTSDREN | |
| SCHEMBL24257004 | 0.68 | CA12 (0.42) | SYKCTSSCTSKPSENEN | |
| SCHEMBL24130775 | 0.68 | KLK5 (0.53) | SYKKLK5CTSSCTSKIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |