Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377254 | 0.93 | SYK (0.39) | SYK | |
| SCHEMBL10378291 | 0.84 | LTA4H (0.39) | LTA4HSYKEPORHDAC1PSMB5 | |
| SCHEMBL10378284 | 0.81 | LTA4H (0.45) | LTA4HSYKHDAC1PSMB5PSMB1 | |
| SCHEMBL7328746 | 0.76 | SYK (0.38) | SYK | |
| SCHEMBL7323172 | 0.74 | SYK (0.43) | LTA4HSYKPSMB5PSMB1PSMB9 | |
| SCHEMBL7320169 | 0.74 | LTA4H (0.43) | LTA4HEPORFFAR1FFAR4LTB4R | |
| SCHEMBL7330559 | 0.71 | LTA4H (0.34) | LTA4HEPORPSMB5PSMB1PSMB9 | |
| SCHEMBL7322402 | 0.71 | TPSAB1 (0.38) | EPOR | |
| SCHEMBL7322023 | 0.70 | TLR2 (0.33) | — | |
| SCHEMBL31724393 | 0.69 | SYK (0.54) | LTA4HSYKHDAC1YAP1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |