Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724249 | 0.77 | PDE3B (0.55) | PKMPDE3BPDE3AKMT2ATHRB | |
| Nitric Acid SCHEMBL16699970 | 0.76 | KDM4E (0.45) | PKMMBD2KMT2AMEN1THRB | |
| SCHEMBL10460856 | 0.74 | CYP1A2 (0.38) | PKMKMT2AMEN1THRBALDH1A1 | |
| SCHEMBL17279787 | 0.73 | PDE3B (0.48) | PKMPDE3BPDE3AKMT2AMEN1 | |
| SCHEMBL8818820 | 0.71 | PDE10A (0.41) | PDE3A | |
| SCHEMBL1303977 | 0.71 | PTGS2 (0.63) | PDE3BPDE3AKMT2AMEN1ALDH1A1 | |
| SCHEMBL63286 | 0.70 | ALDH1A1 (0.59) | PKMKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8830111 | 0.70 | KDM4E (0.49) | PKMKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2834854 | 0.70 | PDE3B (0.49) | PKMPDE3BPDE3AKMT2AMEN1 | |
| SCHEMBL8818815 | 0.69 | CYP2C9 (0.53) | PKMALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008168-A1 | METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS | KEEHAN DONALD J (US) | 1990-07-26 | — | — | WO | disclosed |