SCHEMBL10380920

SCHEMBL10380920

COc1c(F)c(F)c(OC)c(C#N)c1C#N

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
SQOR Q9Y6N5 8/20 0.33
ADORA1 P30542 3/20 0.33
ADORA2A P29274 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
RECQL P46063 1/20 0.31
TRPV4 Q9HBA0 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960238 0.88 LMNA (0.32) LMNAMAPTCYP2C9SQORADORA1
SCHEMBL10619225 0.88 LMNA (0.32) LMNAMAPTCYP2C9SQORADORA1
SCHEMBL10721123 0.87 HSD17B10 (0.32) RECQLTRPV4
SCHEMBL7976156 0.87 LMNA (0.33) LMNAMAPTCYP2C9SQORADORA1
SCHEMBL14314915 0.85 KDM4E (0.33) LMNAMAPTCYP2C9SQORKDM4E
SCHEMBL7870115 0.85 HSD17B10 (0.32)
SCHEMBL29518830 0.77 SLC6A3 (0.36) LMNAMAPTCYP2C9SQORADORA1
SCHEMBL186103 0.77 SLC6A3 (0.36) LMNAMAPTCYP2C9SQORADORA1
SCHEMBL18212328 0.76 IMPDH2 (0.37) LMNAMAPTCYP2C9KDM4EMEN1
SCHEMBL5930636 0.75 RECQL (0.34) LMNAMAPTCYP2C9SQORADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080055-B2 Photoelectric conversion device using TiOF2 as semiconductor SOLVAY SA (BE) 2015-07-14 US disclosed
US-9080055-B2 Photoelectric conversion device using TiOF2 as semiconductor SOLVAY SA (BE) 2015-07-14 US disclosed
US-20130291930-A1 Photoelectric conversion device using TiOF2 as semiconductor SOLVAY SA (BE) 2013-11-07 US disclosed
US-20130291930-A1 Photoelectric conversion device using TiOF2 as semiconductor SOLVAY SA (BE) 2013-11-07 US disclosed
WO-2012172107-A1 DYES, METHOD OF MAKING THEM, AND THEIR USE IN DYE SENSITIZED SOLAR CELLS SOLVAY SA (BE) 2012-12-20 WO disclosed
WO-2012095524-A1 PHTHALOCYANINE DYES, METHOD OF MAKING THEM, AND THEIR USE IN DYE SENSITIZED SOLAR CELLS SOLVAY SA (BE) 2012-07-19 WO disclosed