Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496823 | 0.99 | SIGMAR1 (0.45) | SIGMAR1HDAC9EBPCXCR5 | |
| SCHEMBL27330956 | 0.92 | SIGMAR1 (0.49) | SIGMAR1EBP | |
| SCHEMBL16116728 | 0.82 | HDAC9 (0.44) | SIGMAR1HDAC9 | |
| SCHEMBL19259384 | 0.78 | SIGMAR1 (0.52) | SIGMAR1EBPOPRM1OPRD1OPRK1 | |
| SCHEMBL29609212 | 0.77 | HDAC9 (0.45) | SIGMAR1HDAC9 | |
| SCHEMBL2597839 | 0.77 | HDAC9 (0.45) | SIGMAR1HDAC9 | |
| SCHEMBL7782520 | 0.76 | SIGMAR1 (0.54) | SIGMAR1EBPOPRM1OPRD1OPRK1 | |
| SCHEMBL7788022 | 0.76 | SIGMAR1 (0.54) | SIGMAR1EBPOPRM1OPRD1OPRK1 | |
| SCHEMBL22175918 | 0.76 | SIGMAR1 (0.50) | SIGMAR1EBP | |
| SCHEMBL6751391 | 0.76 | HDAC9 (0.44) | SIGMAR1HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276729-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2011-01-26 | — | — | EP | disclosed |