Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | FURIN | P09958 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381625 | 1.00 | BACE1 (0.50) | BACE1OPRL1FURINOPRK1ERAP2 | |
| SCHEMBL31243860 | 0.92 | KISS1R (0.52) | OPRL1OPRK1 | |
| SCHEMBL30769625 | 0.89 | OPRK1 (0.56) | BACE1OPRK1 | |
| SCHEMBL31257028 | 0.88 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL30019046 | 0.88 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL30799561 | 0.88 | BACE1 (0.54) | BACE1OPRK1CTSD | |
| SCHEMBL31181197 | 0.88 | BACE1 (0.54) | BACE1OPRK1CTSD | |
| SCHEMBL30512642 | 0.87 | BACE1 (0.57) | BACE1OPRL1CTSD | |
| SCHEMBL30407529 | 0.87 | OPRK1 (0.56) | FURINOPRK1ERAP2LNPEP | |
| SCHEMBL30497071 | 0.87 | GNPAT (0.58) | FURINOPRK1ERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990012031-A1 | SOLUBLE CD4 PRODUCED IN $i(E. COLI) | THE UPJOHN COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |