Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009427 | 0.81 | THRB (0.47) | LIPETHRBMAPK1LMNASCN9A | |
| SCHEMBL24750256 | 0.81 | LIPE (0.45) | LIPETHRBMAPK1LMNASCN9A | |
| SCHEMBL31694825 | 0.81 | LIPE (0.45) | LIPETHRBMAPK1LMNASCN9A | |
| SCHEMBL10382692 | 0.81 | RAB9A (0.51) | LIPELMNAMAPTNPSR1 | |
| SCHEMBL10382411 | 0.77 | FFAR1 (0.49) | KCNH2 | |
| SCHEMBL15740415 | 0.77 | TDP1 (0.51) | MAPK1MAPT | |
| SCHEMBL15727613 | 0.77 | TDP1 (0.51) | MAPK1MAPT | |
| SCHEMBL10381933 | 0.75 | THRB (0.56) | LIPETHRBMAPK1LMNASCN9A | |
| SCHEMBL24751486 | 0.73 | LIPE (0.41) | LIPEMAPK1LMNAMAPTNPSR1 | |
| SCHEMBL31009454 | 0.73 | LIPE (0.41) | LIPEMAPK1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1093584-A | — | — | None | — | — | JP | disclosed |
| US-4911754-A | A 5-phenylindolin-2-one compound | AMERICAN CYANAMID COMPANY (US) | 1990-03-27 | — | — | US | disclosed |
| JP-H0193584-A | HERBICIDALLY ACTIVE ARYLOXY SATURATED 5-MEMBERED BENZO FUSED HETERO-CYCLIC COMPOUND | AMERICAN CYANAMID CO | 1989-04-12 | — | — | JP | disclosed |
| EP-0299446-A1 | Herbicidally active arloxy saturated 5-membered benzo fused hetero-cyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1989-01-18 | — | — | EP | disclosed |