Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA3 | P07451 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383654 | 0.88 | CA12 (0.50) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10382795 | 0.86 | LMNA (0.40) | SMN1; SMN2ALDH1A1CA12CA1CA2 | |
| SCHEMBL10383118 | 0.84 | KDM4E (0.42) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL11542934 | 0.83 | SMN1; SMN2 (0.56) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9631239 | 0.73 | CA1 (0.56) | L3MBTL1CA12CA1CA2CA3 | |
| SCHEMBL10383655 | 0.73 | CA1 (0.46) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| Water SCHEMBL10383299 | 0.73 | CA1 (0.45) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10383649 | 0.72 | ALDH1A1 (0.34) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL11541849 | 0.71 | ALDH1A1 (0.56) | CYP1A2TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10382475 | 0.71 | CA1 (0.48) | TSHRSMN1; SMN2ALDH1A1L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |