Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA7 | P43166 | 7/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10383299 | 0.99 | CA1 (0.45) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10382475 | 0.89 | CA1 (0.48) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10383118 | 0.88 | KDM4E (0.42) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10383100 | 0.86 | PTPN1 (0.38) | KMT2AALDH1A1MEN1SMN1; SMN2LMNA | |
| SCHEMBL9630225 | 0.83 | CA1 (0.65) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10383654 | 0.83 | CA12 (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10383649 | 0.74 | ALDH1A1 (0.34) | CA1CA2CA7CA13CA12 | |
| SCHEMBL10382813 | 0.73 | CYP1A2 (0.43) | CA1CA2CA7CA13CA12 | |
| SCHEMBL2982932 | 0.72 | MAPT (0.51) | CA1CA2KMT2AALDH1A1MEN1 | |
| SCHEMBL2982929 | 0.72 | MAPT (0.51) | CA1CA2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |