Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383102 | 0.90 | LMNA (0.37) | PTPN1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10383118 | 0.87 | KDM4E (0.42) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10383655 | 0.86 | CA1 (0.46) | LMNAALDH1A1KMT2AMEN1MAPT | |
| Water SCHEMBL10383299 | 0.85 | CA1 (0.45) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10382795 | 0.85 | LMNA (0.40) | PTPN1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9630165 | 0.84 | CA1 (0.47) | PTPN1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10384354 | 0.81 | MPO (0.41) | PTPN1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10382475 | 0.76 | CA1 (0.48) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9630193 | 0.74 | CA1 (0.49) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10382771 | 0.73 | CA1 (0.44) | LMNAALDH1A1MAPTSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |