Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10382582 | 0.91 | KDM4E (0.40) | TP53NR4A2KCNH2PDE4BKDM4E | |
| SCHEMBL9538214 | 0.81 | NR4A2 (0.42) | TP53NR4A2KCNH2PDE4BPDE4D | |
| Oxalic Acid SCHEMBL9535458 | 0.81 | MAPT (0.43) | TP53NR4A2KCNH2KDM4EMAPT | |
| Oxalic Acid SCHEMBL9535461 | 0.81 | MAPT (0.43) | TP53NR4A2KCNH2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9536739 | 0.80 | NR4A2 (0.41) | TP53NR4A2KCNH2PDE4BPDE4D | |
| SCHEMBL9536526 | 0.80 | NR4A2 (0.47) | TP53NR4A2KCNH2PDE4BKDM4E | |
| SCHEMBL9537472 | 0.79 | NOS2 (0.53) | KDM4EMAPTALDH1A1TSHRHSD17B10 | |
| Oxalic Acid SCHEMBL9539772 | 0.79 | MAPT (0.42) | TP53NR4A2KCNH2PDE4BUSP2 | |
| Oxalic Acid SCHEMBL9539776 | 0.79 | MAPT (0.42) | TP53NR4A2KCNH2PDE4BUSP2 | |
| SCHEMBL10383260 | 0.78 | TP53 (0.46) | TP53NR4A2KCNH2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |