Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9536739 | 0.99 | NR4A2 (0.41) | NR4A2KCNH2TP53PDE4BPDE4D | |
| SCHEMBL10383150 | 0.87 | ALOX15 (0.46) | NR4A2KCNH2TP53LMNAALDH1A1 | |
| SCHEMBL9536526 | 0.83 | NR4A2 (0.47) | NR4A2KCNH2TP53PDE4BPDE4D | |
| Oxalic Acid SCHEMBL9534482 | 0.83 | SSTR5 (0.49) | KCNH2TP53LMNAALDH1A1HPGD | |
| Oxalic Acid SCHEMBL9539776 | 0.82 | MAPT (0.42) | NR4A2KCNH2TP53PDE4BPDE4D | |
| Oxalic Acid SCHEMBL9539772 | 0.82 | MAPT (0.42) | NR4A2KCNH2TP53PDE4BPDE4D | |
| SCHEMBL10383151 | 0.81 | TP53 (0.41) | NR4A2KCNH2TP53PDE4BPDE4D | |
| Oxalic Acid SCHEMBL10383157 | 0.81 | SSTR5 (0.47) | KCNH2TP53LMNAALDH1A1HPGD | |
| Oxalic Acid SCHEMBL9535458 | 0.80 | MAPT (0.43) | NR4A2KCNH2TP53OPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9535461 | 0.80 | MAPT (0.43) | NR4A2KCNH2TP53OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |