SCHEMBL10384239

SCHEMBL10384239

CCNC(C)(C)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.50
SRC P12931 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
HTR1A P08908 1/20 0.44
CYP2D6 P10635 1/20 0.44
SCN1A P35498 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SCN5A Q14524 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
KCNN4 O15554 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19305003 0.98 CES1 (0.48) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL10384830 0.85 TDP1 (0.56) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL10384246 0.82 NAAA (0.49) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL27558300 0.81 CES1 (0.45) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL9680444 0.81 NAAA (0.47) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL10385877 0.81 POLB (0.46) CES1TDP1MEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL19305016 0.81 NAAA (0.47) CES1TDP1HTR1ACYP2D6SCN1A
SCHEMBL11107515 0.80 ADRB2 (0.48) CES1SRCTDP1HTR1ACYP2D6
SCHEMBL10384826 0.78 CES1 (0.56) CES1SRCTDP1MEN1KMT2A
SCHEMBL14819911 0.78 CES1 (0.43) CES1SRCTDP1HTR1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP claimed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
US-4960746-A A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed