Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384239 | 0.81 | CES1 (0.50) | POLBKDM4EGAALMNAMAPT | |
| Hydrochloric Acid SCHEMBL19305003 | 0.80 | CES1 (0.48) | POLBKDM4EGAALMNAMAPT | |
| SCHEMBL11197754 | 0.76 | CES2 (0.46) | POLBKDM4EALDH1A1GAACTDSP1 | |
| SCHEMBL198250 | 0.74 | CES2 (0.54) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL17187854 | 0.74 | CES2 (0.54) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL20363332 | 0.73 | MEN1 (0.54) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8031369 | 0.73 | CES2 (0.48) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10887646 | 0.72 | CES2 (0.52) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3443593 | 0.72 | CES2 (0.52) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL194732 | 0.72 | CES2 (0.52) | POLBKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |