Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384436 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HTTCA2MAPT | |
| SCHEMBL31236761 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HTTMEN1KMT2AMASP2 | |
| SCHEMBL5528949 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HTTMEN1KMT2AMASP2 | |
| SCHEMBL10385158 | 0.72 | TSHR (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL29948478 | 0.71 | VCAM1 (0.47) | ALDH1A1MAPTLMNA | |
| SCHEMBL18147782 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL10384428 | 0.71 | ALDH1A1 (0.68) | ALDH1A1HTTMEN1KMT2AMASP2 | |
| SCHEMBL6941298 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL23875742 | 0.70 | HTR6 (0.39) | ALDH1A1KMT2AMAPT | |
| SCHEMBL30058082 | 0.70 | HTR6 (0.39) | ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935443-A | N-substituted-3-nitro-4-(ureidooxymethyl)-benzenesulfonamides as radiation enhancers | MERCK & CO., INC. (US) | 1990-06-19 | — | — | US | disclosed |