Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468686 | 0.82 | MEN1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9381046 | 0.82 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4DTOP2A | |
| SCHEMBL9380265 | 0.82 | MEN1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9379083 | 0.81 | TOP2A (0.46) | TOP2ATOP2BPARP1KDM4EMAPT | |
| SCHEMBL9378888 | 0.80 | TOP2A (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9378032 | 0.80 | CYP3A4 (0.42) | TOP2ATOP2BKDM4EMAPTGAA | |
| SCHEMBL29468653 | 0.80 | TNKS (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9377152 | 0.80 | KDM4E (0.42) | TOP2ATOP2BKDM4EMAPTRAB9A | |
| SCHEMBL9383971 | 0.76 | MEN1 (0.43) | TOP2ATOP2BKDM4EMAPTRAB9A | |
| SCHEMBL9381632 | 0.76 | TOP2A (0.39) | TOP2ATOP2BTNKS2PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940714-A | 2-substituted carbonylimidazo[4,5-c]quinolines | SHIONOGI & CO., LTD. (JP) | 1990-07-10 | — | — | US | claimed |