Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468686 | 1.00 | MEN1 (0.48) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL29468653 | 0.85 | TNKS (0.42) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL9379249 | 0.83 | TSHR (0.44) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9383971 | 0.82 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10385249 | 0.82 | DAGLA (0.44) | KMT2AALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL9377152 | 0.80 | KDM4E (0.42) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL9381046 | 0.80 | LMNA (0.44) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9379083 | 0.79 | TOP2A (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL30782682 | 0.79 | BRD4 (0.55) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL689576 | 0.79 | BRD4 (0.55) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329073-B1 | 2-Substituted carbonylimidazo[4,5-c]quinolines | SHIONOGI & CO (JP) | 1994-12-28 | — | — | EP | disclosed |