Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468653 | 0.83 | TNKS (0.42) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL9379083 | 0.82 | TOP2A (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9378888 | 0.81 | TOP2A (0.42) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL9378032 | 0.81 | CYP3A4 (0.42) | KDM4EALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL29468686 | 0.80 | MEN1 (0.48) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL9380265 | 0.80 | MEN1 (0.48) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL24642364 | 0.80 | JAK1 (0.42) | — | |
| SCHEMBL10385249 | 0.80 | DAGLA (0.44) | KDM4EALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL9383971 | 0.77 | MEN1 (0.43) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL9381046 | 0.77 | LMNA (0.44) | KDM4EALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329073-B1 | 2-Substituted carbonylimidazo[4,5-c]quinolines | SHIONOGI & CO (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4940714-A | 2-substituted carbonylimidazo[4,5-c]quinolines | SHIONOGI & CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |