SCHEMBL10385264

SCHEMBL10385264

CCOC(O)(Oc1ccccc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.42
PPARA Q07869 3/20 0.42
PIN1 Q13526 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALOX15 P16050 1/20 0.37
POLB P06746 1/20 0.37
CASP6 P55212 1/20 0.37
PKM P14618 1/20 0.37
ELANE P08246 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6040935 0.76 LTA4H (0.39) PPARGPPARALMNAL3MBTL1RAB9A
SCHEMBL34466536 0.74 SRC (0.50) LMNAMAPK1RAB9ANPC1HPGD
SCHEMBL17653510 0.74 PPARG (0.42) PPARGPPARAADORA3L3MBTL1ALOX15
SCHEMBL1960387 0.74 PPARG (0.62) PPARGPPARAADORA3L3MBTL1ELANE
SCHEMBL4752621 0.74 PPARG (0.42) PPARGPPARAADORA3L3MBTL1ALOX15
SCHEMBL10875975 0.73 LTA4H (0.37) PPARGPIN1LMNARAB9ANPC1
SCHEMBL10875977 0.73 LTA4H (0.37) PPARGPIN1LMNARAB9ANPC1
SCHEMBL11780388 0.72 MAPT (0.44) PPARAPIN1L3MBTL1RAB9ANPC1
SCHEMBL9290995 0.72 MAPT (0.38) PPARGPIN1L3MBTL1RAB9ANPC1
Ethyl Acetate SCHEMBL4395006 0.72 ALDH1A1 (0.49) PPARGPPARAPIN1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4956443-A Polyester from hydroxyethoxyphenoxy acetic acid with improve gas barrier properties EASTMAN KODAK COMPANY (US) 1990-09-11 US disclosed