Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078741 | 0.82 | TLR8 (0.32) | TLR8TLR7L3MBTL1MEN1GAA | |
| SCHEMBL27953685 | 0.78 | TLR8 (0.46) | TLR8TLR7L3MBTL1GAAKDM4E | |
| Ethirimol SCHEMBL8818899 | 0.74 | TLR8 (0.41) | TLR8TLR7L3MBTL1MEN1GAA | |
| Ethirimol SCHEMBL20692 | 0.74 | TLR8 (0.41) | TLR8TLR7L3MBTL1MEN1GAA | |
| SCHEMBL11621518 | 0.71 | LMNA (0.46) | TLR8TLR7KMT2AKDM4ELMNA | |
| Bupirimate SCHEMBL22961 | 0.69 | TLR8 (0.33) | TLR8TLR7L3MBTL1GAACA1 | |
| Bupirimate SCHEMBL29394855 | 0.69 | TLR8 (0.33) | TLR8TLR7L3MBTL1GAACA1 | |
| SCHEMBL28707607 | 0.69 | MAPT (0.33) | TLR8TLR7L3MBTL1GAAKDM4E | |
| Bupirimate SCHEMBL29177491 | 0.69 | TLR8 (0.32) | TLR8TLR7L3MBTL1GAAHTT | |
| Bupirimate SCHEMBL6008749 | 0.69 | TLR8 (0.32) | TLR8TLR7L3MBTL1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910200-A | Agricultural fungicide | CELAMERCK GMBH & CO. KG (DE) | 1990-03-20 | — | — | US | disclosed |