Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bupirimate SCHEMBL29394855 | 0.76 | TLR8 (0.33) | MAPTTLR8TLR7KDM4ECYP1A2 | |
| Bupirimate SCHEMBL22961 | 0.76 | TLR8 (0.33) | MAPTTLR8TLR7KDM4ECYP1A2 | |
| Bupirimate SCHEMBL29177491 | 0.75 | TLR8 (0.32) | MAPTTLR8TLR7CYP1A2CYP2C19 | |
| Bupirimate SCHEMBL6008749 | 0.75 | TLR8 (0.32) | MAPTTLR8TLR7CYP1A2CYP2C19 | |
| SCHEMBL27953685 | 0.74 | TLR8 (0.46) | TLR8TLR7KDM4ECYP1A2CYP2C19 | |
| SCHEMBL3078741 | 0.70 | TLR8 (0.32) | TLR8TLR7CYP1A2CYP2C19GAA | |
| SCHEMBL10386403 | 0.69 | TLR8 (0.35) | TLR8TLR7KDM4EGAAL3MBTL1 | |
| SCHEMBL11621518 | 0.68 | LMNA (0.46) | MAPTTLR8TLR7KDM4ECYP1A2 | |
| Ethirimol SCHEMBL20692 | 0.68 | TLR8 (0.41) | MAPTTLR8TLR7KDM4ECYP1A2 | |
| Ethirimol SCHEMBL8818899 | 0.68 | TLR8 (0.41) | MAPTTLR8TLR7KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181158-A | Device and method for producing bupirimate in continuous kettle manner | 江西禾益化工股份有限公司 | 2022-03-15 | — | — | CN | disclosed |