Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DNM2 | P50570 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386403 | 0.82 | TLR8 (0.35) | TLR8TLR7GAAL3MBTL1ALDH1A1 | |
| SCHEMBL27953685 | 0.74 | TLR8 (0.46) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Bupirimate SCHEMBL29394855 | 0.71 | TLR8 (0.33) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Bupirimate SCHEMBL22961 | 0.71 | TLR8 (0.33) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Ethirimol SCHEMBL20692 | 0.70 | TLR8 (0.41) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Ethirimol SCHEMBL8818899 | 0.70 | TLR8 (0.41) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Bupirimate SCHEMBL29177491 | 0.70 | TLR8 (0.32) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| SCHEMBL28707607 | 0.70 | MAPT (0.33) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| Bupirimate SCHEMBL6008749 | 0.70 | TLR8 (0.32) | TLR8TLR7GAAL3MBTL1CYP1A2 | |
| SCHEMBL11621518 | 0.68 | LMNA (0.46) | TLR8TLR7CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180007908-A1 | Pesticidal Mixtures | BASF SE (DE) | 2018-01-11 | — | — | US | disclosed |
| US-9247744-B2 | Ternary pesticidal mixtures | BASF SE (DE) | 2016-02-02 | — | — | US | disclosed |
| US-20160007609-A1 | Pesticidal Mixtures | BASF SE (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-1909579-B1 | FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES | BASF SE (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20150080215-A1 | TERNARY PESTICIDAL MIXTURES | BASF SE (DE) | 2015-03-19 | — | — | US | disclosed |
| US-20140155263-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | BASF SE (DE) | 2014-06-05 | — | — | US | disclosed |
| US-8679514-B2 | Fungicidal mixtures based on azolopyrimidinylamines | BASF SE (DE) | 2014-03-25 | — | — | US | disclosed |
| EP-2489266-A2 | Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide | BASF SE (DE) | 2012-08-22 | — | — | EP | disclosed |
| EP-2489267-A2 | Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide | BASF SE (DE) | 2012-08-22 | — | — | EP | disclosed |
| EP-2489268-A2 | Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide | BASF SE (DE) | 2012-08-22 | — | — | EP | disclosed |
| US-4374143-A | AS FUNGICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-02-15 | — | — | US | disclosed |
| EP-0065334-A1 | New pyrazoline derivatives, method of preparing the new compounds, as well as insecticidal compositions on the basis of these compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-11-24 | — | — | EP | disclosed |
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |
| US-4341548-A | N-(2-Cyclohexylphenyl)-N',N'-diethyl-ethylene diamine, algicidal compositions containing same, and method of use | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-07-27 | — | — | US | disclosed |
| EP-0001663-B1 | NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-05-12 | — | — | EP | disclosed |
| EP-0041298-A2 | Composition for inhibiting or preventing the development of suckers in tobacco plants | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-12-09 | — | — | EP | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |
| EP-0031173-A1 | New nitrothiophenes, method of preparing the new compounds, as well as fungicidal and/or bactericidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-07-01 | — | — | EP | disclosed |
| US-4221801-A | 2-CYANO-5-NITRO-THIAZOLE | DUPHAR INTERNATIONAL RESEARCH (NL) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007609-A1 | Pesticidal Mixtures | PTMS, THOP1, MLN | TLR8 3955/4885TLR7 4553/4885GAA 864/4885 |
| US-20180007908-A1 | Pesticidal Mixtures | PTMS, THOP1, MLN | TLR8 3955/4885TLR7 4553/4885GAA 864/4885 |
| US-20140155263-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | DDT, STS, ARSA | TLR8 4174/4885TLR7 3449/4885GAA 1285/4885 |
| US-20150080215-A1 | TERNARY PESTICIDAL MIXTURES | AADAC, AS3MT, DDT | TLR8 4544/4885TLR7 3714/4885GAA 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.