Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388083 | 0.89 | LTA4H (0.50) | NQO1PDK2MAPTL3MBTL1PTGS2 | |
| SCHEMBL16855936 | 0.88 | NQO1 (0.42) | NQO1PDK2TSHRTDP1MAPT | |
| SCHEMBL16852406 | 0.86 | HMOX1 (0.43) | NQO1PDK2TDP1MAPTL3MBTL1 | |
| SCHEMBL20275274 | 0.85 | FFAR4 (0.48) | NQO1TDP1MAPTL3MBTL1PTGS2 | |
| SCHEMBL27990156 | 0.85 | PTGS2 (0.54) | NQO1PDK2TSHRMAPTL3MBTL1 | |
| SCHEMBL16855821 | 0.85 | MAPT (0.41) | NQO1PDK2MAPTL3MBTL1PTGS2 | |
| SCHEMBL16855927 | 0.85 | MEN1 (0.41) | NQO1TSHRMAPTMEN1NPC1 | |
| SCHEMBL1547853 | 0.84 | NQO1 (0.56) | NQO1TSHRTDP1MAPTFFAR1 | |
| SCHEMBL19998338 | 0.83 | FFAR1 (0.43) | NQO1PTGS2FFAR1FFAR4NPC1 | |
| SCHEMBL9223505 | 0.82 | FFAR4 (0.46) | NQO1TDP1MAPTPTGS2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895986-A | CHEMICAL INTERMEDIATE | COMMISSARIAT A L'ENERGIE (FR) | 1990-01-23 | — | — | US | disclosed |
| US-4795579-A | 2,2'-difluoro-4-alkoxy-4'-hydroxydiphenyls and their derivatives, their production process and their use in liquid crystal display devices | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1989-01-03 | — | — | US | disclosed |