Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694254 | 0.85 | CTSL (0.43) | CTSLDRD2ALDH1A1 | |
| SCHEMBL13515896 | 0.82 | TAAR1 (0.40) | DRD2DRD3ALDH1A1 | |
| SCHEMBL24450547 | 0.81 | ESR1 (0.37) | ALDH1A1 | |
| SCHEMBL7241941 | 0.78 | GRIN2B (0.33) | HTR2CHTR2BCTSL | |
| SCHEMBL12296552 | 0.78 | IDO1 (0.36) | — | |
| SCHEMBL21003868 | 0.77 | GABRA1 (0.40) | ALOX5GPR84ALDH1A1 | |
| SCHEMBL24197475 | 0.77 | SIGMAR1 (0.45) | HTR2BDRD3 | |
| SCHEMBL25569811 | 0.76 | AKR1B1 (0.36) | CTSLALDH1A1 | |
| SCHEMBL24197473 | 0.76 | SLC6A4 (0.46) | — | |
| SCHEMBL24988631 | 0.75 | GABRA1 (0.33) | CNR1HTR2BCTSLALOX5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963580-A | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1990-10-16 | — | — | US | disclosed |