Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445371 | 0.92 | KCNH2 (0.67) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL22874534 | 0.83 | PARP10 (0.66) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL5667052 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL21568937 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL17712563 | 0.81 | SMN1; SMN2 (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL169753 | 0.81 | SMN1; SMN2 (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL22967393 | 0.81 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL1073540 | 0.81 | SYK (0.68) | KDM4EALDH1A1SMN1; SMN2PARP10CYP1A2 | |
| SCHEMBL31688873 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 | |
| SCHEMBL30361386 | 0.81 | PARP10 (0.64) | KDM4EALDH1A1SMN1; SMN2PARP10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943584-A | (p-Phenoxyphenoxy)-methyl-five-membered hetaryls | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |