Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 4/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310925 | 0.86 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL1073540 | 0.85 | SYK (0.68) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL169753 | 0.85 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| Ammonia Solution, Strong SCHEMBL23291159 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL6445371 | 0.84 | KCNH2 (0.67) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL22874534 | 0.83 | PARP10 (0.66) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL16093378 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL22967626 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL21568937 | 0.81 | KDM4E (0.63) | ALDH1A1SMN1; SMN2KDM4EPARP10NPC1 | |
| SCHEMBL10388636 | 0.81 | KDM4E (0.63) | ALDH1A1SMN1; SMN2KDM4EPARP10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-01-10 | — | — | US | disclosed |
| US-20210040114-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF | ACCSALUS BIOSCIENCES LIMITED (VG) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | WNK1, WNK2, WNK3 | ALDH1A1 1467/4885SMN1; SMN2 3866/4885KDM4E 2166/4885 |
| US-20210040114-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF | WNK1, WNK2, WNK3 | ALDH1A1 1467/4885SMN1; SMN2 3866/4885KDM4E 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.