Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202268 | 0.87 | TDO2 (0.38) | HTR2ASLC6A4CA1CA2CHRM2 | |
| SCHEMBL6760397 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL6758783 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL167383 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL235557 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL1797128 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL6759465 | 0.85 | LIPG (0.44) | HTR2ASLC6A4ACHESLC6A2 | |
| SCHEMBL6364753 | 0.84 | HTR2A (0.37) | HTR2AHRH1MAOATLR8SLC6A4 | |
| SCHEMBL3425449 | 0.84 | LIPG (0.41) | HTR2AACHE | |
| SCHEMBL1199989 | 0.81 | HTR2A (0.59) | HTR2AHRH1MAOASLC6A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897092-A | GAS SEPARATION; ALKYLATED BIS-ANILINE MONOMERS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |