SCHEMBL7202268

SCHEMBL7202268

OCCCCCc1cccc2c1C(CCCCCO)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.38
HTR2A P28223 1/20 0.37
JAK2 O60674 1/20 0.33
CYSLTR2 Q9NS75 2/20 0.33
CYSLTR1 Q9Y271 2/20 0.33
TBXAS1 P24557 2/20 0.33
LIPG Q9Y5X9 1/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
ADRA1A P35348 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167383 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL6759465 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL6760397 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL10388652 0.87 HTR2A (0.43) HTR2ACHRM2HTR1AADRA2ACHRM1
SCHEMBL235557 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL6758783 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL1797128 0.87 LIPG (0.44) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL3425449 0.85 LIPG (0.41) HTR2ACYSLTR2CYSLTR1LIPGACHE
SCHEMBL2306813 0.84 TDO2 (0.47) TDO2HTR2AKMT2ACA1CA2
SCHEMBL31275339 0.84 TDO2 (0.47) TDO2HTR2AKMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181639-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY THEREOF KANEKA CORP (JP) 2019-07-03 EP claimed
US-20170190909-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2017-07-06 US claimed
EP-3181639-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY THEREOF Kaneka Corporation (JP) 2017-06-21 EP claimed
EP-0854891-B1 PROCESS FOR PREPARING COATED PLASTIC SURFACES DOW GLOBAL TECHNOLOGIES INC (US) 2003-05-28 EP claimed
EP-0852592-B1 THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL DOW CHEMICAL CO (US) 1999-05-06 EP claimed
EP-0852592-A1 THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL THE DOW CHEMICAL COMPANY (US) 1998-07-15 EP claimed
US-5718967-A PLASMA POLYMERIZED ORGANOSILICON COMPOUNDS; LIQUID CRYSTAL DISPLAY DEVICES THE DOW CHEMICAL COMPANY (US) 1998-02-17 US claimed
WO-1997011980-A1 THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL THE DOW CHEMICAL COMPANY (US) 1997-04-03 WO claimed
US-5574092-A MELT PROCESSABILITY THE DOW CHEMICAL COMPANY (US) 1996-11-12 US claimed
US-10745553-B2 Thermoplastic resin composition and molded article thereof KANEKA CORPORATION (JP) 2020-08-18 US disclosed
EP-3181639-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY THEREOF KANEKA CORP (JP) 2019-07-03 EP disclosed
US-20170190909-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2017-07-06 US disclosed
EP-3181639-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY THEREOF Kaneka Corporation (JP) 2017-06-21 EP disclosed
EP-1060214-B1 COMPOSITIONS CONTAINING A POLYARYLENE ETHER AND A DISPERSIBLE REACTIVE SOLVENT AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2003-07-23 EP disclosed
EP-0852592-A1 THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL THE DOW CHEMICAL COMPANY (US) 1998-07-15 EP disclosed
US-5718967-A PLASMA POLYMERIZED ORGANOSILICON COMPOUNDS; LIQUID CRYSTAL DISPLAY DEVICES THE DOW CHEMICAL COMPANY (US) 1998-02-17 US disclosed
WO-1997031057-A1 POLYMER COMPOSITE AND A METHOD FOR ITS PREPARATION THE DOW CHEMICAL COMPANY (US) 1997-08-28 WO disclosed
WO-1997013802-A1 COATED PLASTIC SUBSTRATE THE DOW CHEMICAL COMPANY (US) 1997-04-17 WO disclosed
WO-1997011980-A1 THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL THE DOW CHEMICAL COMPANY (US) 1997-04-03 WO disclosed
US-5574092-A MELT PROCESSABILITY THE DOW CHEMICAL COMPANY (US) 1996-11-12 US disclosed