Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804016 | 0.90 | ALDH1A1 (0.44) | HPGDHIF1AHSD17B10ALDH1A1TP53 | |
| SCHEMBL15169995 | 0.80 | TNNI3 (0.66) | HPGDHSD17B10ALDH1A1CYP3A4RECQL | |
| SCHEMBL8066094 | 0.78 | MPL (0.49) | HPGDHIF1AHSD17B10ALDH1A1NSD2 | |
| SCHEMBL13818469 | 0.77 | CASP6 (0.54) | HPGDHIF1AHSD17B10ALDH1A1TP53 | |
| SCHEMBL4651295 | 0.77 | CASP6 (0.69) | HPGDHIF1AHSD17B10ALDH1A1TP53 | |
| SCHEMBL11837949 | 0.77 | TNNI3 (0.67) | HPGDHIF1AHSD17B10ALDH1A1TP53 | |
| SCHEMBL2131894 | 0.76 | ALDH1A1 (0.54) | HPGDHIF1AHSD17B10ALDH1A1THRB | |
| SCHEMBL9066446 | 0.75 | NT5E (0.58) | HPGDHSD17B10ALDH1A1CYP3A4THRB | |
| SCHEMBL10573597 | 0.74 | HPGD (0.44) | HPGDHIF1AHSD17B10ALDH1A1TP53 | |
| SCHEMBL29074448 | 0.74 | ALDH1A1 (0.47) | HPGDHIF1AHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0301350-A2 | Disazo dyes | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |
| US-4602084-A | Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component | CIBA-GEIGY CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| US-4129736-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4079051-A | 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4033944-A | Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |