SCHEMBL9066446

SCHEMBL9066446

Nc1ccc2ccc(S(=O)(=O)O)c(O)c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.58
CASP6 P55212 4/20 0.46
NSD2 O96028 2/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
PTPN11 Q06124 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.42
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 4/20 0.41
HSD17B10 Q99714 4/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CTRB1 P17538 1/20 0.41
RECQL P46063 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028738 0.89 CASP6 (0.54) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7790474 0.84 NT5E (0.57) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9334347 0.84 NT5E (0.56) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL8066094 0.81 MPL (0.49) NT5ECASP6NSD2ALDH1A1TDP1
SCHEMBL2131894 0.80 ALDH1A1 (0.54) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL28600231 0.79 NT5E (0.51) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL11595457 0.79 NT5E (0.50) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7898477 0.79 NT5E (0.58) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL342572 0.79 CTDSP1 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL30532025 0.79 CTDSP1 (0.55) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432941-B1 Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions EXXON CHEMICAL PATENTS INC (US) 1996-04-17 EP disclosed
WO-1996002624-A1 A CLEANING KIT AND A CLEANING COMPOSITION AND METHODS OF USE SO-SAFE SPECIALTY PRODUCTS PTY. LTD. (AU) 1996-02-01 WO disclosed
EP-0377166-B1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AG (DE) 1994-03-02 EP disclosed
EP-0432941-A2 Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1991-06-19 EP disclosed
EP-0241104-B1 FIBER-REACTIVE MONOAZO COMPOUND HAVING 7-SUBSTITUTED AMINO-1-NAPHTHOL-SULFONIC ACID AS COUPLING COMPONENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-19 EP disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed
EP-0241104-A1 Fiber-reactive monoazo compound having 7-substituted amino-1-naphthol-sulfonic acid as coupling component SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed
US-4123428-A COLORFASTNESS SANDOZ LTD. (CH) 1978-10-31 US disclosed
US-3933423-A Azoic dyeing of leather E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US disclosed