Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388267 | 0.74 | HMGCR (0.42) | ALDH1A1ALOX15KDM4ECYP1A2MAPT | |
| SCHEMBL2788382 | 0.72 | ALDH1A1 (0.58) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL1045964 | 0.72 | ALDH1A1 (0.58) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL17227584 | 0.72 | VHL (0.34) | ALDH1A1KDM4EHPGDHTTCA2 | |
| SCHEMBL6305769 | 0.70 | CA2 (0.38) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL38604 | 0.70 | ALOX15 (1.00) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL19865370 | 0.69 | ERN1 (0.35) | TYR | |
| Methane SCHEMBL28686923 | 0.67 | ALOX15 (0.94) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL31310910 | 0.67 | ALOX15 (0.94) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL67854 | 0.67 | ALOX15 (0.82) | ALDH1A1ALOX15SMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963580-A | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1990-10-16 | — | — | US | claimed |
| US-4963580-A | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1990-10-16 | — | — | US | disclosed |