Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 6/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841495 | 0.85 | KDR (0.59) | KDRGRM4RAPGEF4PDK1TRPV1 | |
| SCHEMBL16883686 | 0.81 | KIF11 (0.44) | — | |
| SCHEMBL9725601 | 0.78 | KDR (0.43) | RAPGEF3KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL11525237 | 0.78 | KDR (0.43) | RAPGEF3KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL19089350 | 0.78 | AR (0.45) | RAPGEF3KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL11414045 | 0.78 | KDR (0.47) | RAPGEF3KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL18358703 | 0.77 | GRM4 (0.47) | KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL20656067 | 0.76 | RAPGEF3 (0.41) | RAPGEF3KDRGRM4RAPGEF4PDK1 | |
| SCHEMBL10255934 | 0.74 | MAPT (0.53) | RAPGEF4LMNA | |
| SCHEMBL20655719 | 0.74 | AR (0.49) | RAPGEF3KDRGRM4RAPGEF4PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4936892-A | HERBICIDES; PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4909832-A | Plant growth regulator | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4764202-A | 5-dichloroacetamido-4-nitro-1-aryl-pyrazoles, composition containing them, and herbicidal and plant growth regulating method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |