Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389367 | 0.84 | HSP90AA1 (0.40) | CYP2D6SUMO2SUMO1SENP7SENP3 | |
| SCHEMBL10389371 | 0.83 | LMNA (0.45) | CYP2D6GAAKDM4EALDH1A1MPL | |
| SCHEMBL10390196 | 0.78 | HSP90AA1 (0.43) | CYP2D6SUMO2SUMO1SENP7SENP3 | |
| SCHEMBL9806959 | 0.77 | HSP90AA1 (0.47) | SLC40A1GAAKDM4EALDH1A1HKDC1 | |
| SCHEMBL41541 | 0.76 | CYP2D6 (0.53) | CYP2D6SUMO2SUMO1SENP7SENP3 | |
| Toluene SCHEMBL28191312 | 0.76 | CYP2D6 (0.48) | CYP2D6SUMO2SUMO1SENP7SENP3 | |
| SCHEMBL10390245 | 0.75 | HTR6 (0.63) | CYP2D6ALDH1A1HKDC1CTRB1HTR6 | |
| SCHEMBL4897459 | 0.75 | CYP2D6 (0.51) | CYP2D6GAAALDH1A1CTRB1MPL | |
| SCHEMBL8835967 | 0.75 | CYP2D6 (0.51) | CYP2D6GAAALDH1A1CTRB1MPL | |
| SCHEMBL2242476 | 0.75 | CYP2D6 (0.51) | CYP2D6SUMO2SUMO1SENP7SENP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |