Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389247 | 0.90 | PLAU (0.45) | KEAP1NFE2L2EP300MEN1KMT2A | |
| SCHEMBL10389286 | 0.81 | PLAU (0.43) | KEAP1NFE2L2MEN1KMT2ATDP1 | |
| SCHEMBL10389341 | 0.77 | SLC40A1 (0.39) | HKDC1ALDH1A1KDM4EGAASLC40A1 | |
| SCHEMBL10388956 | 0.75 | PLAU (0.47) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL9806976 | 0.74 | PGR (0.48) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL10389371 | 0.73 | LMNA (0.45) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9299326 | 0.73 | ALDH1A1 (0.51) | HSP90AA1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10390245 | 0.71 | HTR6 (0.63) | HKDC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30238204 | 0.71 | KEAP1 (0.61) | HSP90AA1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL10389342 | 0.71 | KMT2A (0.58) | KEAP1NFE2L2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071968-A | Lightfastness, compatibility with other dyes | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0388353-A1 | Azodyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |