Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039350 | 1.00 | REN (0.33) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1037890 | 0.94 | REN (0.31) | REN | |
| SCHEMBL1037889 | 0.94 | REN (0.31) | REN | |
| SCHEMBL1039410 | 0.93 | RORC (0.34) | REN | |
| SCHEMBL1039409 | 0.93 | RORC (0.34) | REN | |
| SCHEMBL1039803 | 0.92 | REN (0.34) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1036295 | 0.91 | REN (0.32) | REN | |
| SCHEMBL1036447 | 0.91 | REN (0.33) | REN | |
| SCHEMBL1036449 | 0.91 | REN (0.33) | REN | |
| SCHEMBL1038043 | 0.90 | RORC (0.32) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |