Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039410 | 1.00 | RORC (0.34) | RORCRENLMNA | |
| SCHEMBL1040451 | 0.93 | REN (0.33) | RORCREN | |
| SCHEMBL1039352 | 0.93 | REN (0.33) | REN | |
| SCHEMBL1039350 | 0.93 | REN (0.33) | REN | |
| SCHEMBL1040452 | 0.93 | REN (0.33) | RORCREN | |
| SCHEMBL1039803 | 0.92 | REN (0.34) | RENLMNA | |
| SCHEMBL1036447 | 0.91 | REN (0.33) | RORCREN | |
| SCHEMBL1036449 | 0.91 | REN (0.33) | RORCREN | |
| SCHEMBL1037890 | 0.90 | REN (0.31) | REN | |
| SCHEMBL1037889 | 0.90 | REN (0.31) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |